Buclizine HCl

CAS No. 129-74-8

Buclizine HCl ( —— )

Catalog No. M17929 CAS No. 129-74-8

Buclizine HCl is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
50MG 27 In Stock
100MG 38 In Stock
200MG 50 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Buclizine HCl
  • Note
    Research use only, not for human use.
  • Brief Description
    Buclizine HCl is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities.
  • Description
    Buclizine HCl is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine binds to and blocks the histamine H1 receptor, thereby preventing the symptoms that are caused by histamine activity. Buclizine exerts its anti-emetic effect by binding to and blocking the muscarinic and histamine receptors in the vomiting center of the central nervous system (CNS). This may prevent activation of the chemoreceptor trigger zone (CTZ) and may reduce nausea and vomiting.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    HT; Cholinergic
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    129-74-8
  • Formula Weight
    505.95
  • Molecular Formula
    C28H33ClN2·2HCl
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    CC(C)(C)c1ccc(cc1)CN1CCN(CC1)C(c1ccccc1)c1ccc(cc1)Cl.Cl.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mostafa GA, et al. Profiles Drug Subst Excip Relat Methodol, 2011, 36:1-33.
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